Scientific Papers

MycoKey aims to unlock new knowledge and to valorize existing knowledge and data by rapid dissemination to research partners and stakeholders in the chain.
In the MycoKey programme all scientific peer reviewed publications are available through open access. Research data will be deposited in public data repositories for (re)-analysis exploitation and dissemination free of charge.
In this page you can find publications describing the scientific results arising from project’s activities.

A Review of Current Methods for Analysis of Mycotoxins in Herbal Medicines

The presence of mycotoxins in herbal medicines is an established problem throughout the entire world. The sensitive and accurate analysis of mycotoxin in complicated matrices (e.g., herbs) typically involves challenging sample pretreatment procedures and an efficient detection instrument. However, although numerous reviews have been published regarding the occurrence of mycotoxins in herbal medicines, few of them provided a detailed summary of related analytical methods for mycotoxin determination. This review focuses on analytical techniques including sampling, extraction, cleanup, and detection for mycotoxin determination in herbal medicines established within the past ten years. Dedicated sections of this article address the significant developments in sample preparation, and highlight the importance of this procedure in the analytical technology. This review also summarizes conventional chromatographic techniques for mycotoxin qualification or quantitation, as well as recent studies regarding the development and application of screening assays such as enzyme-linked immunosorbent assays, lateral flow immunoassays, aptamer-based lateral flow assays, and cytometric bead arrays. The present work provides a good insight regarding the advanced research that has been done and closes with an indication of future demand for the emerging technologies.

Authors: Lei Zhang , Xiao-Wen Dou 1 Cheng Zhang , Antonio F. Logrieco , Mei-Hua Yang
Keywords:  chromatographic methods; herbal medicines; mycotoxin; rapid detection method; sample pretreatment; sampling
Published: 02/02/2018

This work was supported  by the National Key R&D Program of China (2016YFE0112900), EU project H2020-E.U.3.2-678781-MycoKey, CAMS Innovation Fund for Medical Sciences (CIFMS, 2016-I2M-1-012, 2017-I2M-1-013), and National Project for Standardization of Chinese Materia Medica (ZYBZH-Y-JIN-34). CC-BY license